“we have observed that luteolin is a potent fructokinase inhibitor in vitro (IC50: 11.2 μM) and in human proximal tubular cells that express fructokinase”
“we observed that luteolin induced a significant elevation in urinary fructose levels”
Andres-Hernando, A., Li, N., Cicerchi, C. et al. Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice. Nat Commun 8, 14181 (2017). https://doi.org/10.1038/ncomms14181